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In the process of high performance liquid chromatography, especially in the multi-component gradient elution, the gas dissolved in the mobile phase escapes in the form of bubbles when it is mixed, which not only affects the separation efficiency of the chromatographic column, but also affects the stability of the detector baseline and reduces the sensitivity. The principle of quiksep dg-230 degasser is that the mobile phase enters into the degasser through the inlet of the online degasser. In the independent unit vacuum pump cavity, the vacuum pump operates continuously at low speed through the preset vacuum degree. Under the action of the pump, the HPLC mobile phase flows through a short Teflon ? AF degassing membrane tube in the real cavity. According to Henry's law, under the vacuum action, the solvent dissolves The gas is discharged through the pipe wall.